Sammanställning
av de rapporterade CEA - Collie Eye Anomaly Test for Tollers
, se Optigens hemsida för mer information om
testet.
Limits to All Genetic Testing
"There are basic limits for any and all DNA genetic tests. Whether a test is mutation-based or marker-based, it identifies only the specific mutation being tested or the association between a specific marker set and the disease. For example, a mutation test detects one specific mutation in one specific gene. If there are several different mutations or several different genes that can cause the same condition, one must discover and then test for each mutation and each gene. Likewise, a marker test uses one marker or set of markers to define a specific condition. If the condition is associated with several different marker combinations, one must discover and then test for each marker combination. It can be difficult or even impossible to know how many mutations or how many marker sets exist in all the members of a specific breed. As more and more dogs are tested, previously unknown variations may come to light.
In the case of CEA/CH, the OptiGen genetic test for the listed breeds is a mutation-based test."
Nu finns 715 Normal, 153 Carrier, 22 Affected
på listan.
Updated on September 19, 2009
Av My Sköld
E-post: my.skold @ bredband.net
| Expected Results of Breeding Strategies for Inherited Recessive Diseases | |||
| Parent 1 Genotype |
Parent 2 Genotype | ||
| Normal | Carrier | Affected | |
| Normal | All = Normal | 1/2 = Normal 1/2 = Carriers |
All = Carriers |
| Carrier | 1/2 = Normal 1/2 = Carriers |
1/4 = Normal 1/2 = Carriers 1/4 = Affected |
1/2 = Carriers 1/2 = Affected |
| Affected | All = Carriers | 1/2 = Carriers 1/2 = Affected |
All = Affected |